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The woman behind the next big thing in cancer treatment
  + stars: | 2024-02-20 | by ( Katie Hunt | ) edition.cnn.com   time to read: +12 min
Christine Olsson/AFP/Getty ImagesWu’s research focused on small mutations in cancer tumor cells. However, in many cases, cancer vaccines have failed to live up to their promise — largely because the right target hasn’t been found. “This is a fantastic discovery.”By sequencing DNA from healthy and cancer cells, Wu and her team identified a cancer patient’s unique tumor neoantigens. More work is needed before they are a viable treatment options for many cancer patients. To show that these type of cancer vaccines work, much larger randomized control trials are needed.
Persons: Catherine Wu, Boston’s Dana, , , Wu, Lendahl, Dr Patrick Ott, Sam Ogden, Honjo, James Allison, Tasuku Honjo, James P Allison, Christine Olsson, ” Hans, Gustaf Ljunggren, Matt Stone, “ I’m, ” Wu, ” Lendahl, you’ve, It’s, ” Barbara Brigham, BioNTech, ” CNN’s Brenda Goodman Organizations: CNN, Farber Cancer Institute, Royal Swedish Academy of Sciences, Karolinska, Getty, US Food and Drug Administration, FDA, MediaNews, Boston Herald, Merck, Moderna, , Covid Locations: Sweden, BioNTech, Rome
The Indian Council of Medical Research (ICMR) conducted a study following what it called "anecdotal reports about sudden unexplained deaths among apparently healthy adults" aged 18 to 45 between October 2021 and March 2023. "We found no evidence of a positive association of COVID-19 vaccination with unexplained sudden death among young adults," the research group said in a study published in the Indian Journal of Medical Research. "At the same time, family history of sudden death, hospitalisation for COVID-19 and lifestyle behaviours such as recent binge drinking and vigorous-intensity physical activity were risk factors for unexplained sudden death." ICMR researchers identified 29,171 sudden deaths and scrutinised the records of 729 of the cases as well as 2,916 "control" subjects as part of their investigation, the group said. Many Indian hospitals ran out of beds during the peak of the COVID crisis and many people died at home.
Persons: Asmita Koladiya, Jiyanshi Gaurang, Amit Dave, Krishna N, Robert Birsel Organizations: REUTERS, Indian, of Medical Research, Thomson Locations: Lodhida, Rajkot district, Gujarat, India, DELHI, COVID
Editor’s note: A version of this story appeared in CNN’s Wonder Theory science newsletter. Also this week, a new telescope opened our eyes to a fresh perspective of the universe. ESAThe first five images captured by the Euclid telescope showcase glimmering clusters of galaxies and stars. The telescope, launched in July, was designed to create the most detailed 3D map of the hidden “dark side” of the universe. Sign up here to receive in your inbox the next edition of Wonder Theory, brought to you by CNN Space and Science writers Ashley Strickland and Katie Hunt.
Persons: James Webb, Chandra, Lucy, Campi, Alessandro Carboni ​, Alessandro Carboni, Tibor Litauszki, Galatée, Farouk El, Baz, Yardangs, Leif Ristroph, Ristroph, Koji Murata, Andy Murray’s, Ashley Strickland, Katie Hunt Organizations: CNN, Orion, ESA, Hemisphere, New York University’s Courant, Mathematical Sciences, ” Kyoto, CNN Space, Science Locations: Italy, Naples, Capri, Ischia, Bay, Hungarian, Europe, New York, Sardinia, China
Scientists create chimeric monkey with two sets of DNA
  + stars: | 2023-11-09 | by ( Katie Hunt | ) edition.cnn.com   time to read: +7 min
CNN —Scientists based in China have created a monkey chimera with two sets of DNA, experimental work they say could ultimately benefit medical research and the conservation of endangered species. It’s the world’s first live birth of a primate chimera created with stem cells, the researchers said. Scientists have created mouse embryos that are part human, and in 2021, scientists reported that they had grown human-monkey chimeric embryos. In September, researchers reported that they had grown kidneys containing mostly human cells inside pig embryos. Then they selected a subset of cells to inject into genetically distinct 4- to 5-day-old embryos from the same monkey species.
Persons: , , Miguel Esteban, chimeras, Zhen Liu, Liu, Jun Wu, hadn’t, Wu wasn’t, Jacob Hanna, ” Hanna, Penny Hawkins, Organizations: CNN —, Cell, Guangzhou Institute of Biomedicine, Chinese Academy of Sciences, Research, University of Texas Southwestern Medical Center, Weizmann Institute of Science, Royal Society for, National Academies of Sciences, Engineering, Medicine, Covid Locations: China, Health, Research Hangzhou, Israel, United States
DUBLIN (AP) — Rugby will use mouthguard technology as part of its efforts to detect brain injuries suffered by players on the field. World Rugby said it is investing 2 million euros ($2.1 million) in the technology to support unions, competitions and clubs. “The advances in smart mouthguard technology mean elite players will be better cared for than ever before. In community rugby, players should not return to play after a diagnosed brain injury for 21 days. The Rugby World Cup is taking place against the backdrop of a lawsuit filed by former international rugby players against governing bodies, including World Rugby, contending rugby authorities failed to take reasonable action to protect the players from repeated blows to the head during their careers.
Persons: Eanna Falvey Organizations: DUBLIN, , Rugby, Elite, World Rugby, rugby, AP Rugby
REUTERS/Michelle McLoughlin/File PhotoNEW YORK, Aug 4 (Reuters) - A divided federal appeals court on Friday rejected a challenge to a Connecticut law that ended the state's decades-old religious exemptions from immunization requirements for children in schools, colleges and day care. Circuit Court of Appeals in Manhattan said ending religious exemptions, while still allowing medical exemptions, was a rational means to promote health and safety by reducing the potential spread of vaccine-preventable diseases. He said many U.S. courts have reviewed vaccination mandates for children that lack religious exemptions, and only one, in Mississippi, has ever found constitutional problems. Five other U.S. states--California, Maine, Mississippi, New York and West Virginia--also lack religious exemptions. Connecticut's law, signed by Governor Ned Lamont, does not apply to children from kindergarten to 12th grade who previously had received religious exemptions.
Persons: Michelle McLoughlin, Denny Chin, Chin, Barack Obama, Ned Lamont, Joseph Bianco, Donald Trump, Norm Pattis, Brian Festa, William Tong, Lamont, Jonathan Stempel, David Gregorio, Leslie Adler, Deepa Babington Organizations: Pfizer, REUTERS, U.S, Circuit, Patriots USA, CT, Alliance, COVID, Patriots, Connecticut Office, 2nd U.S, Thomson Locations: Storrs , Connecticut, U.S, Connecticut, Manhattan, Mississippi, California , Maine , Mississippi , New York, West Virginia, 2nd, New York
The American Academy of Pediatrics backed gender-related treatments for children on Thursday, reaffirming its position from 2018 on a medical approach that has since been banned in 19 states. But the influential group of doctors also took an extra step of commissioning a systematic review of medical research on the treatments, following similar efforts in Europe that found uncertain evidence for their effectiveness in adolescents. Critics across the political spectrum — including a small but vocal group of pediatricians — have been calling for a closer look at the evidence in recent years, particularly as the number of adolescents who identify as transgender has rapidly increased. The treatments are relatively new, and few studies have tracked their long-term effects. Health bodies in England and Sweden have limited access to the treatments after carrying out systematic reviews, the gold standard for evaluating medical research.
Organizations: American Academy of Pediatrics Locations: Europe, England, Sweden
CNN —President Joe Biden will nominate Dr. Monica Bertagnolli, who currently leads the National Cancer Institute, to be the next director of the National Institutes of Health, the White House announced on Monday. Biden called Bertagnolli “a world-class physician-scientist whose vision and leadership will ensure NIH continues to be an engine of innovation to improve the health of the American people,” in a statement Monday. She would lead the country’s medical research agency, overseeing 27 research institutes and centers focused on different areas of medical research, such as cancer, the human genome, as well as allergy and infectious diseases. The nomination to lead NIH marks a fast ascent within the Biden administration for Bertagnolli. In this August 2022 photo, Monica Bertagnolli, newly appointed director of the National Cancer Institute, stands for recognition during remarks by President Joe Biden.
They promoted and delivered vaccines, developed prevention strategies, monitored data and did a million other unheralded things to help weave a stronger public health safety net. Meanwhile, top health officials are warning that persistent vaccine misinformation remains a serious public health threat. Particularly in vulnerable communities where access to vaccines, therapeutics and good information are lacking, there is much work to be done. And this common-sense principle is still true: When you enact and maintain good policies, good things happen. In the past two weeks, deaths from Covid are up 63%, a possible harbinger of things to come in 2023.
Strep A is surging in the UK and has killed at least 19 kids, the UK Health Security Agency said. A vaccine would be better, but research groups have hit roadblocks during its development. Researchers have been trying to make a strep-A vaccine for decadesIf it's caught in time, strep A can be treated with antibiotics. There is no vaccine commercially available, but several research groups are working on developing one. A GSK spokesperson confirmed to Insider that it's also in the early stages of developing a strep-A vaccine but that it had not started human testing.
BENGALURU, Dec 8 (Reuters) - Around five million people globally have had their data stolen and sold on the bot market till date, of which 600,000 are from India, making it the worst affected country, according to one of the world's largest VPN serice providers NordVPN. Bot markets are used by hackers to sell stolen data from victims' devices with bot malware. NordVPN tracked data for the past four years, ever since bot markets were launched in 2018. read moreNordVPN's study looked into three major bot markets - the Genesis market, the Russian Market, and 2Easy - and found stolen logins including those from Google, Microsoft and Facebook accounts. "What makes bot markets different from other dark web markets is that they are able to get large amounts of data about one person in one place," said Marijus Briedis, chief technology officer at NordVPN.
NEW DELHI — The leading hospital in India’s capital limped back to normalcy on Wednesday after a cyberattack crippled its operations for nearly two weeks. Online registration of patients resumed Tuesday after the hospital was able to access its server and recover lost data. The attack was followed by a series of failed attempts to hack India’s top medical research organization, the Indian Council of Medical Research. “We are digitizing (everything), but then there is an attack on the country’s most important medical institute,” he said. Altaf Qadri / APOn Nov. 30, there were repeated but ultimately unsuccessful attempts to breach the website of the Indian Council of Medical Research, the Press Trust of India news agency reported.
The review, conducted by the National Institute for Health and Care Excellence (NICE) and published on Wednesday, is its first involving COVID-19 treatments as the pandemic enters a new phase. The recommendations are a draft, NICE said, and until final guidance is published, access to COVID-19 medicines will continue as is. NICE acknowledged that there is evidence that Merck's molnupiravir and Gilead Sciences Inc's (GILD.O) hospital-administered antiviral remdesivir are effective at treating COVID-19. It also recommended against three other COVID treatments, including GSK (GSK.L) and partner Vir Biotechnology's (VIR.O) sotrovimab, an antibody therapy that the World Health Organization recommended against in September. One expert said that some of the COVID treatments NICE recommended against are an important part of the British government's current strategy.
Opinion | Science Has a Nasty Photoshopping Problem
  + stars: | 2022-10-29 | by ( Elisabeth Bik | ) www.nytimes.com   time to read: +14 min
One evening in January 2014, I sat at my computer at home, sifting through scientific papers. Manipulated imagery in scientific papers can look ordinary at first glance. However, this ability, combined with my — what some might call obsessive — personality, helped me when hunting duplications in scientific images by eye. So when a scientist’s research shows a negative result, cheating can be tempting. Legitimate criticism of scientific research should receive legal protection.
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